Title : The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN.

Pub. Date : 2007 Sep

PMID : 17876045






6 Functional Relationships(s)
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1 The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN. parthenolide phosphatase and tensin homolog Homo sapiens
2 Transfection of wild-type PTEN into PTEN-null cells, PC3, confers the enhanced radiosensitization effect of parthenolide in PTEN-expressing cells. parthenolide phosphatase and tensin homolog Homo sapiens
3 Transfection of wild-type PTEN into PTEN-null cells, PC3, confers the enhanced radiosensitization effect of parthenolide in PTEN-expressing cells. parthenolide phosphatase and tensin homolog Homo sapiens
4 Transfection of wild-type PTEN into PTEN-null cells, PC3, confers the enhanced radiosensitization effect of parthenolide in PTEN-expressing cells. parthenolide phosphatase and tensin homolog Homo sapiens
5 When PTEN expression is knocked down in DU 145 cells, the cells become more resistant to parthenolide"s effect. parthenolide phosphatase and tensin homolog Homo sapiens
6 The presence of PTEN enhances the radiosensitization effect of parthenolide, in part, by suppressing the absolute amount of activated p-Akt. parthenolide phosphatase and tensin homolog Homo sapiens