Pub. Date : 2007 Dec 15
PMID : 17848616
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We show that PF4/heparin macromolecular assembly occurs through colloidal interactions, wherein heparin facilitates the growth of complexes through charge neutralization. | Heparin | platelet factor 4 | Mus musculus |
| 2 | We show that PF4/heparin macromolecular assembly occurs through colloidal interactions, wherein heparin facilitates the growth of complexes through charge neutralization. | Heparin | platelet factor 4 | Mus musculus |
| 3 | The size of PF4/heparin macromolecules is governed by the molar ratios of the reactants. | Heparin | platelet factor 4 | Mus musculus |
| 4 | Maximal complex size occurs at molar ratios of PF4/heparin at which surface charge is neutral. | Heparin | platelet factor 4 | Mus musculus |
| 5 | These studies suggest that the clinical heterogeneity in the HIT immune response may be due in part to requirements for specific biophysical parameters of the PF4/heparin complexes that occur in settings of intense platelet activation and PF4 release. | Heparin | platelet factor 4 | Mus musculus |
| 6 | These studies suggest that the clinical heterogeneity in the HIT immune response may be due in part to requirements for specific biophysical parameters of the PF4/heparin complexes that occur in settings of intense platelet activation and PF4 release. | Heparin | platelet factor 4 | Mus musculus |