| Protein Name | platelet factor 4 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 56744 |
| Gene Symbol | Pf4 |
| UniProt | Q9Z126 (PLF4_MOUSE), Q3TVN6 (Q3TVN6_MOUSE), Q6P8R3 (Q6P8R3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
59
Total Number of Articles : 71 |
Description |
platelet factor 4 |
| Gene Summary |
Predicted to enable CXCR3 chemokine receptor binding activity; chemokine activity; and heparin binding activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and defense response to protozoan. Located in extracellular matrix. Is expressed in several structures, including blood vessel; bone marrow; central nervous system; liver; and yolk sac. Human ortholog(s) of this gene implicated in multiple myeloma. Orthologous to human PF4 (platelet factor 4) and PF4V1 (platelet factor 4 variant 1). [provided by Alliance of Genome Resources, Jul 2025] |
| synonyms |
|
| Properties | |