Title : Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells.

Pub. Date : 2007 Sep 1

PMID : 17804731






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, using the potent ACC inhibitor soraphen A, a macrocyclic polyketide from myxobacteria, we show that ACC activity in cancer cells is essential for proliferation and survival. Polyketides acetyl-CoA carboxylase alpha Homo sapiens