Title : Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase.

Pub. Date : 2007 Oct 15

PMID : 17804225






2 Functional Relationships(s)
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1 A successful design of conformationally restricted novel quinazolinone derivatives linked via a cyclopentene moiety as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors has been developed. Cyclopentanes poly(ADP-ribose) polymerase 1 Homo sapiens
2 A successful design of conformationally restricted novel quinazolinone derivatives linked via a cyclopentene moiety as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors has been developed. Cyclopentanes poly(ADP-ribose) polymerase 1 Homo sapiens