Title : Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells.

Pub. Date : 2007 Nov

PMID : 17785366






2 Functional Relationships(s)
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1 It was proposed that growth enhancement of leiomyoma cells by progesterone was mediated via bcl-2 induction. Progesterone BCL2 apoptosis regulator Homo sapiens
2 Transient transfection with deletion mutants of bcl-2 promoter showed that the -1281/-258-bp region conferred responsiveness to progesterone induction in the presence of PR-A. Progesterone BCL2 apoptosis regulator Homo sapiens