Pub. Date : 1991 Sep
PMID : 1776464
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TfR staining of the islets was weaker in iron-overloaded rats than in the controls. | Iron | transferrin receptor | Rattus norvegicus |
| 2 | These findings suggest that 1) iron uptake by islet cells in vivo is regulated and mediated by TfR, 2) intracytoplasmic Ft transforms into stainable iron in iron-overloaded rats, and 3) predominance of TfR expression in B cells may result in selective deposition of iron and predispose B cells to damage and diabetes mellitus in iron-overloaded rats. | Iron | transferrin receptor | Rattus norvegicus |