Title : Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: implications for HCV-associated hepatocarcinogenesis.

Pub. Date : 2008 Jan 1

PMID : 17764115






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We further demonstrated that stabilization of PPARalpha through a possible interaction with HCV core protein and an increase in nonesterified fatty acids, which may serve as endogenous PPARalpha ligands, in hepatocyte nuclei contributed to the core protein-specific PPARalpha activation. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus
2 We further demonstrated that stabilization of PPARalpha through a possible interaction with HCV core protein and an increase in nonesterified fatty acids, which may serve as endogenous PPARalpha ligands, in hepatocyte nuclei contributed to the core protein-specific PPARalpha activation. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus
3 We further demonstrated that stabilization of PPARalpha through a possible interaction with HCV core protein and an increase in nonesterified fatty acids, which may serve as endogenous PPARalpha ligands, in hepatocyte nuclei contributed to the core protein-specific PPARalpha activation. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus