Pub. Date : 2007 Oct
PMID : 17728068
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The CCAAT-binding factor CBF/NF-Y regulates the human acetylcholinesterase promoter activity during calcium ionophore A23187-induced cell apoptosis. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | We previously reported that the expression of acetylcholinesterase during A23187-induced apoptosis of HeLa cells is regulated by Ca(2+) mobilization through the modulation of mRNA stability and acetylcholinesterase promoter activity. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | We previously reported that the expression of acetylcholinesterase during A23187-induced apoptosis of HeLa cells is regulated by Ca(2+) mobilization through the modulation of mRNA stability and acetylcholinesterase promoter activity. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | Transactivation of the human acetylcholinesterase promoter by A23187 was partially mediated by the distal CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter, which was bound by the CCAAT binding factor (CBF/NF-Y). | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 5 | Transactivation of the human acetylcholinesterase promoter by A23187 was partially mediated by the distal CCAAT motif within the -1270 to -1248 fragment of the human acetylcholinesterase promoter, which was bound by the CCAAT binding factor (CBF/NF-Y). | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 6 | In the present study, we investigated the molecular mechanisms by which CBF/NF-Y regulates A23187-induced activation of the human acetylcholinesterase promoter. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 7 | Our results suggest that acetylcholinesterase promoter activation during A23187-induced HeLa cell apoptosis may result partly from the dissociation of CBF/NF-Y from the distal CCAAT motif in the acetylcholinesterase promoter, reversing this suppression. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 8 | Our results suggest that acetylcholinesterase promoter activation during A23187-induced HeLa cell apoptosis may result partly from the dissociation of CBF/NF-Y from the distal CCAAT motif in the acetylcholinesterase promoter, reversing this suppression. | Calcimycin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |