Pub. Date : 2007 Jul
PMID : 17718425
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Elevated expression of Bax was obviously observed after DOX treatment, while this elevation was prevented by MT induction by Zinc. | Doxorubicin | BCL2-associated X protein | Mus musculus |
| 2 | CONCLUSION: These findings suggest that metallothionein induced by Zinc exhibits protective effects on the cardiac apoptosis of DOX, which might be mediated through the prevention of Bax protein up-regulation by DOX and associated elevation of Bax/Bcl-2 ratio. | Doxorubicin | BCL2-associated X protein | Mus musculus |
| 3 | CONCLUSION: These findings suggest that metallothionein induced by Zinc exhibits protective effects on the cardiac apoptosis of DOX, which might be mediated through the prevention of Bax protein up-regulation by DOX and associated elevation of Bax/Bcl-2 ratio. | Doxorubicin | BCL2-associated X protein | Mus musculus |
| 4 | CONCLUSION: These findings suggest that metallothionein induced by Zinc exhibits protective effects on the cardiac apoptosis of DOX, which might be mediated through the prevention of Bax protein up-regulation by DOX and associated elevation of Bax/Bcl-2 ratio. | Doxorubicin | BCL2-associated X protein | Mus musculus |