Title : Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion.

Pub. Date : 2007 Nov 15

PMID : 17702895






1 Functional Relationships(s)
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Protein Name
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1 Importantly, silencing of the Rap1 guanine exchange factor CalDAG-GEFI inhibited SDF-1alpha- and phorbol 12-myristate 13-acetate (PMA)-induced adhesion to ICAM-1 while having no effect on adhesion to VCAM-1. Tetradecanoylphorbol Acetate vascular cell adhesion molecule 1 Homo sapiens