Title : Effect of intrathecal NG-nitro-L-arginine methyl ester administration on Fos expression in the spinal dorsal horn in rats following sciatic nerve ligation.

Pub. Date : 2007 Jun

PMID : 17694681






2 Functional Relationships(s)
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1 Effect of intrathecal NG-nitro-L-arginine methyl ester administration on Fos expression in the spinal dorsal horn in rats following sciatic nerve ligation. NG-Nitroarginine Methyl Ester Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 In this study, we examined the effect of intrathecal L-NAME, a non-selective nitric oxide synthase (NOS) inhibitor, on nociceptive behavior and spinal Fos expression in rats following chronic constriction injury (CCI) of sciatic nerve, a model of neuropathic pain similar to that observed in clinical setting. NG-Nitroarginine Methyl Ester Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus