Title : Possible involvement of post-dopamine D2 receptor signalling components in the pathophysiology of schizophrenia.

Pub. Date : 2008 Mar

PMID : 17681085






1 Functional Relationships(s)
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1 Dopamine D2 receptor (DRD2) activation induces a signalling complex of AKT1, PP2A and beta-arrestin2 which dephosphorylates/inactivates AKT1 thereby activating GSK-3beta, transducing dopamine-dependent behaviour. Dopamine arrestin beta 2 Homo sapiens