Title : Fluid shear-induced activation and cleavage of CD18 during pseudopod retraction by human neutrophils.

Pub. Date : 2008 Feb

PMID : 17676580






2 Functional Relationships(s)
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1 Western blot analysis using a CD18 antibody targeted against the intracellular domain revealed reduced levels of full-length CD18 after stimulation of neutrophils with either fluid shear stress or with the Ca2+ ionophore phorbol 12-myristate 13-acetate (PMA; 100 nM) in the presence of exogenous cathepsin B (0.5 U/ml). Tetradecanoylphorbol Acetate integrin subunit beta 2 Homo sapiens
2 Western blot analysis using a CD18 antibody targeted against the intracellular domain revealed reduced levels of full-length CD18 after stimulation of neutrophils with either fluid shear stress or with the Ca2+ ionophore phorbol 12-myristate 13-acetate (PMA; 100 nM) in the presence of exogenous cathepsin B (0.5 U/ml). Tetradecanoylphorbol Acetate integrin subunit beta 2 Homo sapiens