Protein Name integrin subunit beta 2
Organism Homo sapiens
Gene ID 3689
Gene Symbol

ITGB2

UniProt P05107 (ITB2_HUMAN), B4E0R1 (B4E0R1_HUMAN), A0A494C0X7 (A0A494C0X7_HUMAN)
Relationships Total Number of functionally related compound(s) : 404
Total Number of Articles : 532
Description

integrin subunit beta 2

Gene Summary

This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

synonyms
  • integrin beta-2
  • cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor)
  • complement component 3 receptor 3 and 4 subunit
Click to show/hide the synonyms
Properties