Title : Complex interactions between hypoxia inducible factors, insulin-like growth factor-II and oxygen in early murine trophoblasts.

Pub. Date : 2007 Nov-Dec

PMID : 17658597






2 Functional Relationships(s)
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1 Furthermore, expression of Hif-2alpha and the HIF target genes: asHif-1alpha, Vegf and Slc2a1 were reduced under low oxygen with the addition of IGF-II. Oxygen endothelial PAS domain protein 1 Mus musculus
2 In conclusion, Hif-1alpha and Hif-2alpha are differentially regulated by oxygen and IGF-II in cultured trophoblast cells and asHif-1alpha may mediate the response to prolonged hypoxia in murine trophoblasts. Oxygen endothelial PAS domain protein 1 Mus musculus