Title : EGF-like ligands stimulate osteoclastogenesis by regulating expression of osteoclast regulatory factors by osteoblasts: implications for osteolytic bone metastases.

Pub. Date : 2007 Sep 14

PMID : 17636266






1 Functional Relationships(s)
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1 Coculture with bone metastatic breast cancer MDA-MB-231 cells had similar effects on the expression of OPG and MCP1 in the osteoblastic cells, and those effects could be partially abolished by the EGFR inhibitor PD153035. 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline epidermal growth factor receptor Mus musculus