Title : Characterization of the transportation of berberine in Coptidis rhizoma extract through rat primary cultured cortical neurons.

Pub. Date : 2008 Jan

PMID : 17631668






3 Functional Relationships(s)
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1 The results showed that metabolic inhibitor KCN and P-glycoprotein inhibitor verapamil could increase berberine concentration within the neurons, indicating that efflux of berberine was energy-dependent and P-glycoprotein was likely to be involved. Berberine ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
2 The results showed that metabolic inhibitor KCN and P-glycoprotein inhibitor verapamil could increase berberine concentration within the neurons, indicating that efflux of berberine was energy-dependent and P-glycoprotein was likely to be involved. Berberine ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus
3 The results showed that metabolic inhibitor KCN and P-glycoprotein inhibitor verapamil could increase berberine concentration within the neurons, indicating that efflux of berberine was energy-dependent and P-glycoprotein was likely to be involved. Berberine ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus