Title : Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta.

Pub. Date : 2007 Oct

PMID : 17620346






1 Functional Relationships(s)
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1 The in vitro covalent binding was inhibited in the presence of beta-aminopropionitrile, D-penicillamine, and hydralazine, which suggested that the aldehyde group of allysine in human elastin was relevant to the covalent binding. Hydralazine elastin Homo sapiens