Title : Functional polymorphisms of the cytochrome P450 1A2 (CYP1A2) gene and prolonged QTc interval in schizophrenia.

Pub. Date : 2007 Aug 15

PMID : 17611010






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Statistically significant result for CYP1A2(*)1F was noted for all patients receiving chlorpromazine equivalent doses of above 300 mg and also for a further subgroup on antipsychotics known to be CYP1A2 substrates (p=0.007, mean QTc in ms for A/A: 395.5+/-15.1, A/C: 425.7+/-25.1, C/C: 427.3+/-20.7). qtc cytochrome P450 family 1 subfamily A member 2 Homo sapiens