Pub. Date : 2007 May
PMID : 17575397
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway. | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 2 | Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 3 | Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 4 | Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 5 | Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 6 | Surprisingly, the incidence of liver tumors was higher in Pparalpha-null mice exposed to 0.05% DEHP (25.8%) than in similarly exposed wild-type mice (10.0%). | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |
| 7 | The protooncogene c-jun-mRNA was induced, and c-fos-mRNA tended to be induced only in Pparalpha-null mice fed a 0.05% DEHP-containing diet. | Diethylhexyl Phthalate | peroxisome proliferator activated receptor alpha | Mus musculus |