Pub. Date : 2007 Jul-Aug
PMID : 17574387
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: The MPTP treatment significantly depleted striatal glutathione content, reduced the activity of glutathione peroxidase (GPX), superoxide dismutase (SOD), and catalase, increased malondialdehyde level, and elevated interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) levels in striatum (P < 0.05). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | interleukin 6 | Mus musculus |
| 2 | RESULTS: The MPTP treatment significantly depleted striatal glutathione content, reduced the activity of glutathione peroxidase (GPX), superoxide dismutase (SOD), and catalase, increased malondialdehyde level, and elevated interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) levels in striatum (P < 0.05). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | interleukin 6 | Mus musculus |
| 3 | The pre-intake of NAC, SEC, SMC, and SPC significantly attenuated MPTP-induced glutathione loss, retained the activity of GPX and SOD, diminished oxidative stress, and suppressed MPTP-induced elevation of IL-6 and TNF-alpha (P < 0.05). | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | interleukin 6 | Mus musculus |