Pub. Date : 2007 Jul
PMID : 17565271
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of parathyroid hormone mRNA stability by calcium, phosphate and uremia. | Calcium | parathyroid hormone | Rattus norvegicus |
| 2 | Understanding the mechanism by which calcium and phosphate regulate parathyroid hormone gene expression is important for both normal physiology and in pathological states, especially chronic kidney disease. | Calcium | parathyroid hormone | Rattus norvegicus |
| 3 | RECENT FINDINGS: Calcium and phosphate regulate parathyroid hormone secretion, gene expression and, if prolonged, parathyroid cell proliferation. | Calcium | parathyroid hormone | Rattus norvegicus |
| 4 | In the rat, regulation of parathyroid hormone gene expression by calcium, phosphate and uremia is posttranscriptional, affecting mRNA stability. | Calcium | parathyroid hormone | Rattus norvegicus |
| 5 | SUMMARY: Calcium, phosphate and uremia determine parathyroid hormone mRNA stability through the binding of the protective factors adenosine-uridine rich binding factor 1 and Up-stream of N-ras and the recruitment of a degradation complex that cleaves parathyroid hormone mRNA. | Calcium | parathyroid hormone | Rattus norvegicus |
| 6 | SUMMARY: Calcium, phosphate and uremia determine parathyroid hormone mRNA stability through the binding of the protective factors adenosine-uridine rich binding factor 1 and Up-stream of N-ras and the recruitment of a degradation complex that cleaves parathyroid hormone mRNA. | Calcium | parathyroid hormone | Rattus norvegicus |