Title : Correlation between serum brain-derived neurotrophic factor level and an in vivo marker of cortical integrity.

Pub. Date : 2007 Sep 1

PMID : 17560556






4 Functional Relationships(s)
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1 In the present study we hypothesized that serum BDNF concentration is associated with in vivo level of cerebral N-acetylaspartate (NAA), a well established marker of neuronal integrity. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
2 In the present study we hypothesized that serum BDNF concentration is associated with in vivo level of cerebral N-acetylaspartate (NAA), a well established marker of neuronal integrity. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
3 RESULTS: The BDNF serum concentrations were positively associated with the concentrations of NAA (T = 2.193, p = .037) and total choline (T = 1.997, p = .055; trend) but not total creatine or glutamate in the ACC. N-acetylaspartate brain derived neurotrophic factor Homo sapiens
4 CONCLUSIONS: The preliminary data might indicate that BDNF serum concentration reflects some aspects of neuronal plasticity as indicated by its association with NAA level in the cerebral cortex. N-acetylaspartate brain derived neurotrophic factor Homo sapiens