Title : The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis.

Pub. Date : 2007 Jun 15

PMID : 17548652






2 Functional Relationships(s)
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1 The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis. Dinoprostone interleukin 23 subunit alpha Homo sapiens
2 These studies suggest that high levels of PGE(2) exacerbate the inflammatory process through the preferential expression and release of DC-derived IL-23 and the subsequent support of the autoreactive/inflammatory Th17 phenotype. Dinoprostone interleukin 23 subunit alpha Homo sapiens