Title : Regulation of protease-activated receptor (PAR) 1 and PAR4 signaling in human platelets by compartmentalized cyclic nucleotide actions.

Pub. Date : 2007 Aug

PMID : 17525299






1 Functional Relationships(s)
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1 Platelet activation by thrombin and other agonists is broadly inhibited by prostacyclin and nitric oxide acting through adenylyl and guanylyl cyclases to elevate cAMP and cGMP levels, respectively. Nitric Oxide coagulation factor II, thrombin Homo sapiens