Title : AT1 receptor antisense therapy transiently lowers blood pressure in Ren-2 transgenic rats.

Pub. Date : 2007 Jul

PMID : 17521968






1 Functional Relationships(s)
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1 Collectively, the data show a prolonged antihypertensive effect of AT1 receptor antisense oligonucleotides during the developmental phase of hypertension in TGR when applied as a single treatment in prehypertensive animals which, however, does not persist up to the maintenance phase of hypertension in adulthood. Oligonucleotides angiotensin II receptor, type 1a Rattus norvegicus