Pub. Date : 2007 Aug
PMID : 17521393
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mycobacterium tuberculosis H37Rv induces monocytic release of interleukin-6 via activation of mitogen-activated protein kinases: inhibition by N-acetyl-L-cysteine. | Acetylcysteine | interleukin 6 | Homo sapiens |
2 | The aim of this study was to investigate the role of mitogen-activated protein kinases in the secretion of interleukin-6 in THP-1 cells and human primary monocytes that were infected with Mycobacterium tuberculosis H37Rv, and its regulation by N-acetyl-L-cysteine, a potential antimycobacterial agent. | Acetylcysteine | interleukin 6 | Homo sapiens |
3 | Pretreatment with N-acetyl-L-cysteine reduced, in a dose-dependent manner, M. tuberculosis H37Rv-induced activation of mitogen-activated protein kinase kinase 3/6 and interleukin-6 production in THP-1 cells. | Acetylcysteine | interleukin 6 | Homo sapiens |