Title : Oxygen tension controls the expansion of human CNS precursors and the generation of astrocytes and oligodendrocytes.

Pub. Date : 2007 Jul

PMID : 17498968






1 Functional Relationships(s)
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1 We found that in vitro expansion of human postnatal brain CD133(+) nestin(+) precursors is enhanced at 5% oxygen, while raising oxygen tension to 20% depletes precursors and promotes astrocyte differentiation even in the presence of mitogens. Oxygen prominin 1 Homo sapiens