Title : Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening.

Pub. Date : 2007 Apr

PMID : 17477831






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Acetyl-coenzyme A carboxylase (ACC) enzymes exist as two isoforms, ACC1 and ACC2, which play critical roles in fatty acid biosynthesis and oxidation. Fatty Acids acetyl-CoA carboxylase beta Homo sapiens
2 The mitochondrial ACC2 is primarily expressed in heart and skeletal muscle, where it is involved in the regulation of fatty acid oxidation. Fatty Acids acetyl-CoA carboxylase beta Homo sapiens