Title : The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells.

Pub. Date : 2007 Feb

PMID : 17464346






1 Functional Relationships(s)
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1 The increased secretion of TNF-alpha and sICAM-1 and the increased activity of NF-kappaB by ADMA were altered by SB203580 (5 micromol/L) or PD98059 (20 micromol/L), but not by LY294002 (20 micromol/L). SB 203580 nuclear factor kappa B subunit 1 Homo sapiens