Title : Angiotensin II-induced regulation of the expression and localization of iron metabolism-related genes in the rat kidney.

Pub. Date : 2007 Feb

PMID : 17460390






1 Functional Relationships(s)
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1 Real-time polymerase chain reaction (PCR) showed that the mRNA expression of TfR, iron-responsive element-negative DMT1, FPN, and hepcidin mRNA increased ~1.9-fold, ~1.7-fold, ~2.3-fold, and ~4.7-fold, respectively, after angiotensin II infusion as compared with that of untreated controls, and that these increases could be suppressed by the concomitant administration of losartan. Iron transferrin receptor Rattus norvegicus