Title : A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein.

Pub. Date : 2007 May 1

PMID : 17452637






2 Functional Relationships(s)
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1 Here we demonstrate that a prototypical GPCR, the beta2-adrenergic receptor (beta2AR), can be incorporated into a reconstituted high-density lipoprotein (rHDL) phospholipid bilayer particle together with the stimulatory heterotrimeric G protein, Gs. Phospholipids adrenoceptor beta 2 Homo sapiens
2 Here we demonstrate that a prototypical GPCR, the beta2-adrenergic receptor (beta2AR), can be incorporated into a reconstituted high-density lipoprotein (rHDL) phospholipid bilayer particle together with the stimulatory heterotrimeric G protein, Gs. Phospholipids adrenoceptor beta 2 Homo sapiens