Pub. Date : 2007 Sep
PMID : 17443690
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When eNOS protein expression in endothelial cells was significantly decreased by eNOS siRNA treatment, superoxide generation was significantly higher in the MMECs grown in low glucose, but reduced in those grown in high glucose for 72 h. Thus, exposure of MMECs to high glucose results in increased oxidative stress that is associated with increased eNOS and NADPH oxidase subunit expression, notably p22phox, and decreased expression of SOD1 and 3. | Superoxides | superoxide dismutase 1, soluble | Mus musculus |