Pub. Date : 2007 Mar
PMID : 17440226
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PPARalpha agonist induces the accumulation of ceramide in the heart of rats fed high-fat diet. | Ceramides | peroxisome proliferator activated receptor alpha | Rattus norvegicus |
| 2 | To investigate the mechanism of this phenomenon we examined the effects of PPARalpha activation on ceramide metabolism in the myocardium. | Ceramides | peroxisome proliferator activated receptor alpha | Rattus norvegicus |
| 3 | Our results demonstrated that PPARalpha activation modulates myocardial ceramide metabolism and leads to the accumulation of ceramide in the heart of the high-fat fed rats due to its increased synthesis de novo. | Ceramides | peroxisome proliferator activated receptor alpha | Rattus norvegicus |
| 4 | Our results demonstrated that PPARalpha activation modulates myocardial ceramide metabolism and leads to the accumulation of ceramide in the heart of the high-fat fed rats due to its increased synthesis de novo. | Ceramides | peroxisome proliferator activated receptor alpha | Rattus norvegicus |