Title : Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum.

Pub. Date : 2007 Aug

PMID : 17437548






2 Functional Relationships(s)
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1 To study the role of the enzyme tyrosine hydroxylase (TH; EC 1.14.16.2) in this experimental paradigm, we have examined its activity by assessing the accumulation of l-3,4-dihydroxyphenylalanine after inhibiting the subsequent enzyme in the DA synthetic pathway, aromatic l-amino acid decarboxylase, with 3-hydroxybenzylhydrazine. Dihydroxyphenylalanine tyrosine hydroxylase Homo sapiens
2 To study the role of the enzyme tyrosine hydroxylase (TH; EC 1.14.16.2) in this experimental paradigm, we have examined its activity by assessing the accumulation of l-3,4-dihydroxyphenylalanine after inhibiting the subsequent enzyme in the DA synthetic pathway, aromatic l-amino acid decarboxylase, with 3-hydroxybenzylhydrazine. Dihydroxyphenylalanine tyrosine hydroxylase Homo sapiens