Protein Name tyrosine hydroxylase
Organism Homo sapiens
Gene ID 7054
Gene Symbol

TH

UniProt P07101 (TY3H_HUMAN), P78428 (P78428_HUMAN)
Relationships Total Number of functionally related compound(s) : 304
Total Number of Articles : 631
Description

tyrosine hydroxylase

Gene Summary

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • tyrosine 3-monooxygenase
  • dystonia 14
  • tyrosine 3-hydroxylase
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Properties