Title : Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats.

Pub. Date : 2007 Aug

PMID : 17431097






1 Functional Relationships(s)
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1 Then, using an acid-induced acute lung injury mouse model, we found that nicotine, choline, and PNU-282,987 (a specific alpha7 nAChR agonist) decreased excess lung water and lung vascular permeability, and reduced protein concentration in the bronchoalveolar lavage (BAL). Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus