Title : Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.

Pub. Date : 2007 May 15

PMID : 17428624






1 Functional Relationships(s)
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1 MNNG-induced DNA damage (measured by the comet assay) and thymocyte death (measured by propidium iodide uptake) was prevented by the PARP inhibitor PJ-34 and by glutathione (GSH) or N-acetylcysteine (NAC). Propidium poly(ADP-ribose) polymerase 1 Homo sapiens