Pub. Date : 2007 Jul
PMID : 17426710
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, over-expression of AC in SCC-1 cells increased resistance to Fas-induced cell killing. | ammonium ferrous sulfate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |
| 2 | Conversely, down-regulation of AC using specific AC small interfering RNA (siRNA) sensitized the SCC-1 cancer cell line to Fas-induced apoptosis. | ammonium ferrous sulfate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |
| 3 | Conversely, down-regulation of AC using specific AC small interfering RNA (siRNA) sensitized the SCC-1 cancer cell line to Fas-induced apoptosis. | ammonium ferrous sulfate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |
| 4 | Finally, we show that the AC inhibitor LCL 204 can sensitize HNSCC cell lines to Fas-induced apoptosis both in vitro and in a xenograft model in vivo, suggesting that the combination of FasL gene therapy and LCL 204 may become a new treatment option for advanced-stage head and neck cancer. | ammonium ferrous sulfate | N-acylsphingosine amidohydrolase 1 | Homo sapiens |