Title : SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK.

Pub. Date : 2007 Apr 17

PMID : 17420479






2 Functional Relationships(s)
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1 Likewise, SLP-76, particularly its N-terminal tyrosines, was required for TCR-induced tyrosine phosphorylation and activation of ITK but was not required for the phosphorylation or activation of ZAP-70. Tyrosine T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens
2 Likewise, SLP-76, particularly its N-terminal tyrosines, was required for TCR-induced tyrosine phosphorylation and activation of ITK but was not required for the phosphorylation or activation of ZAP-70. Tyrosine T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens