Title : Global improvement of vascular function and redox state with low-dose folic acid: implications for folate therapy in patients with coronary artery disease.

Pub. Date : 2007 May 1

PMID : 17420345






2 Functional Relationships(s)
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1 Low-dose folic acid increased nitric oxide-mediated endothelium-dependent vasomotor responses, reduced vascular superoxide production, and improved enzymatic coupling of endothelial nitric oxide synthase through availability of the cofactor tetrahydrobiopterin. Folic Acid nitric oxide synthase 3 Homo sapiens
2 CONCLUSIONS: Low-dose folic acid treatment, comparable to daily intake and dietary fortification, improves vascular function through effects on endothelial nitric oxide synthase and vascular oxidative stress. Folic Acid nitric oxide synthase 3 Homo sapiens