Title : Piperine protects cisplatin-induced apoptosis via heme oxygenase-1 induction in auditory cells.

Pub. Date : 2007 Sep

PMID : 17418561






2 Functional Relationships(s)
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1 Piperine also induced antioxidant response element-luciferase and translocated nuclear factor-E2-related factor-2 (Nrf2) to nucleus. piperine NFE2 like bZIP transcription factor 2 Homo sapiens
2 These results demonstrate that the expression of HO-1 by piperine is mediated by both JNK pathway and Nrf2, and the expression inhibits cisplatin-induced apoptosis in HEI-OC1 cells. piperine NFE2 like bZIP transcription factor 2 Homo sapiens