Pub. Date : 2007 Jan
PMID : 17404062
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 2 | In this article, we have investigated the effects of capsaicin on apoptosis in relation to AMPK activation in colon cancer cell. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 3 | Concomitantly, the activation of AMPK and the increased expression of the inactive form of acetyl-CoA carboxylase (ACC) were detected in capsaicin-treated colon cancer cells. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 4 | We showed that both capsaicin and 5"-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside (AICAR), an AMPK activator possess the AMPK-activating capacity as well as apoptosis-inducing properties. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 5 | We showed that both capsaicin and 5"-aminoimidazole-4-carboxamide-1-beta-D-ribonucleoside (AICAR), an AMPK activator possess the AMPK-activating capacity as well as apoptosis-inducing properties. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 6 | Evidence of the association between AMPK activation and the increased apoptosis in HT-29 colon cancer cells by capsaicin treatment, and further findings of the correlation of the activated AMPK and the elevated apoptosis by cotreatment of AICAR and capsaicin support AMPK as an important component of apoptosis, as well as a possible target of cancer control. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 7 | Evidence of the association between AMPK activation and the increased apoptosis in HT-29 colon cancer cells by capsaicin treatment, and further findings of the correlation of the activated AMPK and the elevated apoptosis by cotreatment of AICAR and capsaicin support AMPK as an important component of apoptosis, as well as a possible target of cancer control. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |
| 8 | Evidence of the association between AMPK activation and the increased apoptosis in HT-29 colon cancer cells by capsaicin treatment, and further findings of the correlation of the activated AMPK and the elevated apoptosis by cotreatment of AICAR and capsaicin support AMPK as an important component of apoptosis, as well as a possible target of cancer control. | Capsaicin | protein kinase AMP-activated catalytic subunit alpha 2 | Homo sapiens |