Pub. Date : 2007
PMID : 17382577
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Exposure of CF to high glucose and EGF increased phosphorylated EGF-R, SGK-1, and fibronectin expression in wild-type cells. | Glucose | epidermal growth factor receptor | Homo sapiens |
| 2 | Inhibition of the EGF-R reduced SGK-1 and fibronectin expression in control, and following exposure to EGF and high glucose conditions. | Glucose | epidermal growth factor receptor | Homo sapiens |
| 3 | CONCLUSION: These results suggest that high glucose induced fibronectin expression is mediated through the EGF-R and downstream expression of SGK-1. | Glucose | epidermal growth factor receptor | Homo sapiens |