Title : Structural basis of aquaporin inhibition by mercury.

Pub. Date : 2007 May 4

PMID : 17376483






1 Functional Relationships(s)
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1 To elucidate the mechanism we designed a mutant, T183C, of aquaporin Z (AqpZ) patterned after the known mercury-sensitive site of aquaporin 1 (AQP1) and determined the X-ray crystal structures of the unbound and mercury blocked states. Mercury aquaporin 1 (Colton blood group) Homo sapiens