Title : Basal ganglia dopamine loss due to defect in purine recycling.

Pub. Date : 2007 May

PMID : 17374562






2 Functional Relationships(s)
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Protein Name
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1 In both humans and mice, deficiency of hypoxanthine-guanine phosphoribosyl transferase (HPRT) is associated with profound loss of striatal dopamine, with relative preservation of other neurotransmitters. Dopamine hypoxanthine guanine phosphoribosyl transferase Mus musculus
2 In both humans and mice, deficiency of hypoxanthine-guanine phosphoribosyl transferase (HPRT) is associated with profound loss of striatal dopamine, with relative preservation of other neurotransmitters. Dopamine hypoxanthine guanine phosphoribosyl transferase Mus musculus