Title : Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?

Pub. Date : 2007 Apr

PMID : 17371237






1 Functional Relationships(s)
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1 Recruitment of the p85-p110 complex to receptors and adaptor proteins via the p85 SH2 (Src homology 2) domains alleviates this inhibition, leading to PI3K activation and production of PIP(3) (phosphatidylinositol 3,4,5-trisphosphate). pip(3) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Mus musculus