Title : The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice.

Pub. Date : 2007 Dec

PMID : 17356567






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Desipramine decreased corticosterone levels in both FVB/N controls and in abcb1ab (-/-) mice, but in abcb1ab (-/-) mice the effects were smaller. Corticosterone ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus