Pub. Date : 2007 Feb 5
PMID : 17355822
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Icariine stimulates proliferation and differentiation of human osteoblasts by increasing production of bone morphogenetic protein 2. | icariin | bone morphogenetic protein 2 | Homo sapiens |
| 2 | BMP-2 mRNA synthesis was elevated significantly in response to Icariine (20 microg/ml). | icariin | bone morphogenetic protein 2 | Homo sapiens |
| 3 | CONCLUSIONS: Icariine has a direct stimulatory effect on the proliferation and differentiation of cultured human osteoblast cells in vitro, which may be mediated by increasing production of BMP-2 in osteoblasts. | icariin | bone morphogenetic protein 2 | Homo sapiens |